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Methods that can simultaneously detect dozens of peptides are becoming standard

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It has been discovered and heavily studied for over 40 years

The primary concern for the FDA was the lack of large-scale, randomized controlled trials, which are the gold standard for new drug approval

Rodent models have contributed significantly to our understanding of synaptic physiology, but growing evidence points to distinctive features of human neurons that are not fully captured in rodents 5 , making direct investigation in human cells essential for studying synaptic pathologies linked to cognitive decline